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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2089202Generated: October 30, 2026

4-Hydroxy-4-thiazol-2-yl-cyclohexanone → HCID 54755558, compound

https://huagongshe.com/reaction/2089202

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Hydroxy-4-thiazol-2-yl-cyclohexanoneHCID 59017437—
ReactantN-azetidin-3-yl-2-(1-ethyl-5-trifluoromethyl-1H-indazol-3-ylamino)-acetamide TFA saltHCID 86660181—
ProductHCID 54755558HCID 54755558—

Reaction Steps

The title compound was prepared as a white solid from reaction of N-azetidin-3-yl-2-(1-ethyl-5-trifluoromethyl-1H-indazol-3-ylamino)-acetamide TFA salt (as prepared in Example 67, Step A) and 4-hydroxy-4-thiazol-2-yl-cyclohexanone using the procedure described in Step E of Example 1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08436023B2
Source datasetuspto-grants-2013_05
ORD IDord-f362ad50e3794a009d3ade78522c7529
Source noteuspto-grants-2013_05