HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 59017431, compound → 2-(1-Ethyl-5-trifluoromethyl-1H-indazol-3-ylamino)-N-{1-[4-hydroxy-4-(2-methyl-thiazol-5-yl)-cyclohexyl]-azetidin-3-yl}-acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 59017431 | HCID 59017431 | — |
| Reactant | N-azetidin-3-yl-2-(1-ethyl-5-trifluoromethyl-1H-indazol-3-ylamino)-acetamide TFA salt | HCID 86660181 | — |
| Product | 2-(1-Ethyl-5-trifluoromethyl-1H-indazol-3-ylamino)-N-{1-[4-hydroxy-4-(2-methyl-thiazol-5-yl)-cyclohexyl]-azetidin-3-yl}-acetamide | HCID 54755559 | — |
Reaction Steps
The title compound was prepared as a white solid from reaction of N-azetidin-3-yl-2-(1-ethyl-5-trifluoromethyl-1H-indazol-3-ylamino)-acetamide TFA salt (as prepared in Example 67, Step A) and 4-hydroxy-4-(2-methyl-thiazol-5-yl)-cyclohexanone using the procedure described in Step E of Example 1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08436023B2 |
| Source dataset | uspto-grants-2013_05 |
| ORD ID | ord-2ae94d1c1c97459fbdc3e818c164e3cb |
| Source note | uspto-grants-2013_05 |