HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(Methoxymethyl)cyclohexan-1-one → 2-[1-(2-Hydroxy-ethyl)-5-trifluoromethyl-1H-indazol-3-ylamino]-N-[1-(4-methoxymethyl-cyclohexyl)-azetidin-3-yl]-acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(Methoxymethyl)cyclohexan-1-one | HCID 57829016 | — |
| Reactant | HCID 86660184 | HCID 86660184 | — |
| Product | 2-[1-(2-Hydroxy-ethyl)-5-trifluoromethyl-1H-indazol-3-ylamino]-N-[1-(4-methoxymethyl-cyclohexyl)-azetidin-3-yl]-acetamide | HCID 54755803 | — |
Reaction Steps
The title compound was prepared as a white solid from reaction of N-azetidin-3-yl-2-[1-(2-hydroxy-ethyl)-5-trifluoromethyl-1H-indazol-3-ylamino]-acetamide TFA salt (as prepared in Example 74, Step A) and 4-methoxymethyl-cyclohexanone using the procedure described in Step E of Example 1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08436023B2 |
| Source dataset | uspto-grants-2013_05 |
| ORD ID | ord-9a3e9bd0499f4129b509d1c354ca49e6 |
| Source note | uspto-grants-2013_05 |