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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2089216Generated: October 31, 2026

4-Hydroxy-4-thiazol-2-yl-cyclohexanone → HCID 54755922, compound

https://huagongshe.com/reaction/2089216

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Hydroxy-4-thiazol-2-yl-cyclohexanoneHCID 59017437—
Reactant3-[(azetidin-3-ylcarbamoylmethyl)-amino]-5-trifluoromethyl-indazole-1-carboxylic acid tert-butyl amide TFA saltHCID 131730555—
ProductHCID 54755922HCID 54755922—

Reaction Steps

The title compound was prepared as a white solid from reaction of 3-[(azetidin-3-ylcarbamoylmethyl)-amino]-5-trifluoromethyl-indazole-1-carboxylic acid tert-butyl amide TFA salt and 4-hydroxy-4-thiazol-2-yl-cyclohexanone using the procedure described in Step E of Example 1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08436023B2
Source datasetuspto-grants-2013_05
ORD IDord-11bd5ddb905c408aa1f8a378eddfe224
Source noteuspto-grants-2013_05