Ethyl 4-oxocyclohexanecarboxylate → HCID 54756156, compound

HRID 2089231Notes

Reaction equation

HRID 2089231 reaction equation
[CH2:1]([N:4]1[C:12]2[C:7](=[CH:8][C:9]([C:13]([F:16])([F:15])[F:14])=[CH:10][CH:11]=2)[C:6]([NH:17][CH2:18][C:19]([NH:21][CH:22]2[CH2:25][NH:24][CH2:23]2)=[O:20])=[N:5]1)[CH:2]=[CH2:3].[CH2:26]([O:28][C:29]([CH:31]1[CH2:36][CH2:35][C:34](=O)[CH2:33][CH2:32]1)=[O:30])[CH3:27]>>[CH2:26]([O:28][C:29]([CH:31]1[CH2:36][CH2:35][CH:34]([N:24]2[CH2:23][CH:22]([NH:21][C:19](=[O:20])[CH2:18][NH:17][C:6]3[C:7]4[C:12](=[CH:11][CH:10]=[C:9]([C:13]([F:16])([F:14])[F:15])[CH:8]=4)[N:4]([CH2:1][CH:2]=[CH2:3])[N:5]=3)[CH2:25]2)[CH2:33][CH2:32]1)=[O:30])[CH3:27]

Participants

3

Reactant 2

HCID 317638Ethyl 4-oxocyclohexanecarboxylateHCID 58548850HCID 58548850, compound

Product 1

HCID 54756156HCID 54756156, compound

Procedure

The title compound was prepared as a white solid from reaction of 2-(1-allyl-5-trifluoromethyl-1H-indazol-3-ylamino)-N-azetidin-3-yl-acetamide and 4-oxo-cyclohexanecarboxylic acid ethyl ester using the procedure described in Step E of Example 1.

Sources & evidence

ORD record
ord-fcbcd74c0b594041bacfe5a08aa7d909
Source dataset
uspto-grants-2013_05
Patent number
US08436023B2

Reaction notes

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