(1,1'-Bicyclohexyl)-4-one → HCID 54756157, compound

HRID 2089232Notes

Reaction equation

HRID 2089232 reaction equation
[CH2:1]([N:4]1[C:12]2[C:7](=[CH:8][C:9]([C:13]([F:16])([F:15])[F:14])=[CH:10][CH:11]=2)[C:6]([NH:17][CH2:18][C:19]([NH:21][CH:22]2[CH2:25][NH:24][CH2:23]2)=[O:20])=[N:5]1)[CH:2]=[CH2:3].[CH:26]1([CH:33]2[CH2:38][CH2:37][CH2:36][CH2:35][CH2:34]2)[CH2:31][CH2:30][C:29](=O)[CH2:28][CH2:27]1>>[CH2:1]([N:4]1[C:12]2[C:7](=[CH:8][C:9]([C:13]([F:16])([F:14])[F:15])=[CH:10][CH:11]=2)[C:6]([NH:17][CH2:18][C:19]([NH:21][CH:22]2[CH2:23][N:24]([CH:36]3[CH2:37][CH2:38][CH:33]([CH:26]4[CH2:31][CH2:30][CH2:29][CH2:28][CH2:27]4)[CH2:34][CH2:35]3)[CH2:25]2)=[O:20])=[N:5]1)[CH:2]=[CH2:3]

Participants

3

Reactant 2

HCID 41690(1,1'-Bicyclohexyl)-4-oneHCID 58548850HCID 58548850, compound

Product 1

HCID 54756157HCID 54756157, compound

Procedure

The title compound was prepared as a white solid from reaction of 2-(1-allyl-5-trifluoromethyl-1H-indazol-3-ylamino)-N-azetidin-3-yl-acetamide and bicyclohexyl-4-one using the procedure described in Step E of Example 1.

Sources & evidence

ORD record
ord-90c153ff86934a1facc896f223a94a55
Source dataset
uspto-grants-2013_05
Patent number
US08436023B2

Reaction notes

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