HRID2089234

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID79488

Cyclohexanone, 4-(1-methylethyl)-

C9H16O

结构：O=C(CNc1nn(Cc2ccccc2)c2ccc(C(F)(F)F)cc12)NC1CNC1

HCID58548869

未命名化合物

PRODUCTS

生成物

结构：CC(C)C1CCC(N2CC(NC(=O)CNc3nn(Cc4ccccc4)c4ccc(C(F)(F)F)cc34)C2)CC1

HCID58548837

未命名化合物

PROCEDURE

实验过程

The title compound was prepared as a white solid from reaction of N-azetidin-3-yl-2-(1-benzyl-5-trifluoromethyl-1H-indazol-3-ylamino)-acetamide and 4-isopropyl-cyclohexanone using the procedure described in Step E of Example 1.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-6b3ab910bf7a4df6a39e4410bcf0d604
来源数据集: uspto-grants-2013_05
DOI: 10.6084/m9.figshare.5104873.v1
专利: US08436023B2
来源说明: uspto-grants-2013_05

反应 SMILES

[NH:1]1[CH2:4][CH:3]([NH:5][C:6](=[O:29])[CH2:7][NH:8][C:9]2[C:17]3[C:12](=[CH:13][CH:14]=[C:15]([C:18]([F:21])([F:20])[F:19])[CH:16]=3)[N:11]([CH2:22][C:23]3[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=3)[N:10]=2)[CH2:2]1.[CH:30]([CH:33]1[CH2:38][CH2:37][C:36](=O)[CH2:35][CH2:34]1)([CH3:32])[CH3:31]>>[CH2:22]([N:11]1[C:12]2[C:17](=[CH:16][C:15]([C:18]([F:20])([F:19])[F:21])=[CH:14][CH:13]=2)[C:9]([NH:8][CH2:7][C:6]([NH:5][CH:3]2[CH2:2][N:1]([CH:36]3[CH2:37][CH2:38][CH:33]([CH:30]([CH3:32])[CH3:31])[CH2:34][CH2:35]3)[CH2:4]2)=[O:29])=[N:10]1)[C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1