HuagongsheHuagongshe Chemistry Print Report · For research reference only
(S)-3-fluoropyrrolidine → HCID 58464744, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (S)-3-fluoropyrrolidine | HCID 7016277 | — |
| Reactant | 5-chloro-1-methyl-4-nitro-1H-pyrazole | HCID 12344836 | — |
| Product | HCID 58464744 | HCID 58464744 | 83% |
Reaction Steps
Reaction of 5-chloro-1-methyl-4-nitro-1H-pyrazole and (S)-3-fluoropyrrolidine gave (S)-5-(3-fluoropyrrolidin-1-yl)-1-methyl-4-nitro-1H-pyrazole as a yellow solid (220 g, 83%). 1H NMR (400 MHz, CDCl3) δ 8.05 (s, 1H), 5.48-5.31 (m, 1H), 3.79 (s, 3H), 3.73-3.57 (m, 2H), 3.49-3.37 (m, 2H), 2.46-2.27 (m, 2H)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08436001B2 |
| Source dataset | uspto-grants-2013_05 |
| ORD ID | ord-8ae066c6249d480daf1fe1aa6b2948b2 |
| Source note | uspto-grants-2013_05 |