HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,4-Diazepan-5-one → 1-(1-methyl-4-nitro-1H-pyrazol-5-yl)-1,4-diazepan-5-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,4-Diazepan-5-one | HCID 2737264 | — |
| Reactant | 5-chloro-1-methyl-4-nitro-1H-pyrazole | HCID 12344836 | — |
| Product | 1-(1-methyl-4-nitro-1H-pyrazol-5-yl)-1,4-diazepan-5-one | HCID 58464930 | 58% |
Reaction Steps
Reaction of 5-chloro-1-methyl-4-nitro-1H-pyrazole and 1,4-diazepan-5-one gave 1-(1-methyl-4-nitro-1H-pyrazol-5-yl)-1,4-diazepan-5-one as a yellow oil (173 mg, 58%). 1H NMR (400 MHz, CDCl3) δ 8.03 (s, 1H), 6.35 (s, 1H), 3.82 (s, 3H), 3.53-3.47 (m, 2H), 3.38-3.31 (m, 4H), 2.83-2.78 (m, 2H)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08436001B2 |
| Source dataset | uspto-grants-2013_05 |
| ORD ID | ord-06c17e2f3a2741faa1b2eebbf841a0cc |
| Source note | uspto-grants-2013_05 |