Morpholine → HCID 68472254, compound

HRID 2089575Notes

Reaction equation

HRID 2089575 reaction equation
C([N:8]1[C:16]2[C:11](=[CH:12][C:13]([CH2:20]Br)=[CH:14][C:15]=2[N+:17]([O-:19])=[O:18])[C:10]([Br:22])=[C:9]1[C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1)(OC(C)(C)C)=O.[NH:29]1[CH2:34][CH2:33][O:32][CH2:31][CH2:30]1>>[Br:22][C:10]1[C:11]2[C:16](=[C:15]([N+:17]([O-:19])=[O:18])[CH:14]=[C:13]([CH2:20][N:29]3[CH2:34][CH2:33][O:32][CH2:31][CH2:30]3)[CH:12]=2)[NH:8][C:9]=1[C:23]1[CH:24]=[CH:25][CH:26]=[CH:27][CH:28]=1

Participants

3

Reactant 2

HCID 8083MorpholineHCID 68472286HCID 68472286, compound

Product 1

HCID 68472254HCID 68472254, compound

Procedure

1-BOC-3-bromo-5-bromomethyl-7-nitro-2-phenyl-indole prepared in Step B of Preparation 47 and morpholine were reacted according to the same procedures as Steps C and D of Preparation 47 to give the title compound.

Workup

  1. customwere reacted
  2. customaccording to the same procedures as Steps C and D of Preparation 47

Sources & evidence

ORD record
ord-d9d7801a0bf6498aa5295e6cc7fb87d1
Source dataset
uspto-grants-2013_05
Patent number
US08436038B2

Reaction notes

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