Cyclopentanone → Cyclopentyl-(5-chloro-3-phenyl-1H-indol-7-yl)-amine

HRID 2089596Notes

Reaction equation

[Cl:1][C:2]1[CH:3]=[C:4]2[C:8](=[C:9]([N+:11]([O-])=O)[CH:10]=1)[NH:7][CH:6]=[C:5]2[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1.[C:20]1(=O)[CH2:24][CH2:23][CH2:22][CH2:21]1>>[CH:20]1([NH:11][C:9]2[CH:10]=[C:2]([Cl:1])[CH:3]=[C:4]3[C:8]=2[NH:7][CH:6]=[C:5]3[C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)[CH2:24][CH2:23][CH2:22][CH2:21]1

Participants

Reactant 2

HCID 8452Cyclopentanone

HCID 684718405-Chloro-3-phenyl-7-nitro-1H-indole

Product 1

HCID 25215446Cyclopentyl-(5-chloro-3-phenyl-1H-indol-7-yl)-amine

Procedure

5-Chloro-7-nitro-3-phenyl-1H-indole prepared in Preparation 41 and cyclopentanone were reacted according to the same procedure as Example 1 to give the title compound.

Workup

customwere reacted

Sources & evidence

ORD record: ord-9672041de67c4c8cbf52fb37810dd752
Source dataset: uspto-grants-2013_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08436038B2

Reaction notes

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