Methanesulfonyl chloride → HCID 25215916, compound

HRID 2089599Notes

Reaction equation

[CH:1]1([NH:6][C:7]2[CH:8]=[C:9]([Cl:23])[CH:10]=[C:11]3[C:15]=2[NH:14][C:13]([C:16]2[CH:21]=[CH:20][C:19]([NH2:22])=[CH:18][CH:17]=2)=[CH:12]3)[CH2:5][CH2:4][CH2:3][CH2:2]1.[CH3:24][S:25](Cl)(=[O:27])=[O:26]>>[Cl:23][C:9]1[CH:10]=[C:11]2[C:15](=[C:7]([NH:6][CH:1]3[CH2:5][CH2:4][CH2:3][CH2:2]3)[CH:8]=1)[NH:14][C:13]([C:16]1[CH:17]=[CH:18][C:19]([NH:22][S:25]([CH3:24])(=[O:27])=[O:26])=[CH:20][CH:21]=1)=[CH:12]2

Participants

Reactant 2

HCID 31297Methanesulfonyl chloride

HCID 25215914HCID 25215914, compound

Product 1

HCID 25215916HCID 25215916, compound

Procedure

Cyclopentyl-[2-(4-aminophenyl)-5-chloro-1H-indol-7-yl]-amine prepared in Example 82 and methanesulfonylchloride were reacted according to the same procedure as Example 22 to give the title compound.

Sources & evidence

ORD record: ord-30e4a7c5c8d14c48bca5e5d1d3a6fbf0
Source dataset: uspto-grants-2013_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08436038B2

Reaction notes

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