Phenyl isocyanate → HCID 25216421, compound

HRID 2089604Notes

Reaction equation

HRID 2089604 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]2[C:8](=[C:9]([NH:11][CH:12]3[CH2:17][CH2:16][NH:15][CH2:14][CH2:13]3)[CH:10]=1)[NH:7][C:6]([C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1)=[CH:5]2.[C:24]1([N:30]=[C:31]=[O:32])[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=1>>[C:24]1([NH:30][C:31]([N:15]2[CH2:14][CH2:13][CH:12]([NH:11][C:9]3[CH:10]=[C:2]([Cl:1])[CH:3]=[C:4]4[C:8]=3[NH:7][C:6]([C:18]3[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=3)=[CH:5]4)[CH2:17][CH2:16]2)=[O:32])[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=1

Participants

3

Reactant 2

HCID 7672Phenyl isocyanateHCID 25216420HCID 25216420, compound

Product 1

HCID 25216421HCID 25216421, compound

Procedure

(5-Chloro-2-phenyl-1H-indol-7-yl)-piperidin-4-yl-amine prepared in Example 93 and phenylisocyanate were reacted according to the same procedure as Example 22 to give the title compound.

Sources & evidence

ORD record
ord-11fced5e0c2d412186181d69a7a8158d
Source dataset
uspto-grants-2013_05
Patent number
US08436038B2

Reaction notes

Loading…