tert-Butyl 2-oxopiperidine-1-carboxylate → HCID 68474729, compound

HRID 2089606Notes

Reaction equation

HRID 2089606 reaction equation
[F:1][C:2]1[CH:3]=[C:4]2[C:8](=[C:9]([N+:11]([O-])=O)[CH:10]=1)[NH:7][C:6]([C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1)=[CH:5]2.C([N:27]1[CH2:32][CH2:31][CH2:30][CH2:29][C:28]1=O)(OC(C)(C)C)=O>>[F:1][C:2]1[CH:3]=[C:4]2[C:8](=[C:9]([NH:11][CH:30]3[CH2:31][CH2:32][NH:27][CH2:28][CH2:29]3)[CH:10]=1)[NH:7][C:6]([C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1)=[CH:5]2

Participants

3

Reactant 2

HCID 7577838tert-Butyl 2-oxopiperidine-1-carboxylateHCID 68474032HCID 68474032, compound

Product 1

HCID 68474729HCID 68474729, compound

Procedure

5-Fluoro-7-nitro-2-phenyl-1H-indole prepared in Preparation 25 and 1-BOC-piperidinone were reacted according to the same procedure as Example 90 to give the title compound.

Workup

  1. customwere reacted

Sources & evidence

ORD record
ord-2e3093cfece941839938143f0e30ff01
Source dataset
uspto-grants-2013_05
Patent number
US08436038B2

Reaction notes

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