2-Bromo-5-methylpyridine → HCID 68476375, compound

HRID 2089614Notes

Reaction equation

HRID 2089614 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]2[C:8](=[C:9]([NH2:11])[CH:10]=1)[NH:7][C:6]([C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1)=[CH:5]2.Br[C:19]1[CH:24]=[CH:23][C:22]([CH3:25])=[CH:21][N:20]=1>>[Cl:1][C:2]1[CH:3]=[C:4]2[C:8](=[C:9]([NH:11][C:19]3[CH:24]=[CH:23][C:22]([CH3:25])=[CH:21][N:20]=3)[CH:10]=1)[NH:7][C:6]([C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1)=[CH:5]2

Participants

3

Reactant 2

HCID 5642162-Bromo-5-methylpyridineHCID 68478397HCID 68478397, compound

Product 1

HCID 68476375HCID 68476375, compound

Procedure

7-Amino-5-chloro-2-phenyl-1H-indole prepared in Example 3 and 2-bromo-5-methyl-pyridine were reacted according to the same procedure as Example 113 to give the title compound.

Sources & evidence

ORD record
ord-140e34361dff4b91a3e7dcf3c65c192c
Source dataset
uspto-grants-2013_05
Patent number
US08436038B2

Reaction notes

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