反应详情

2-[3-(7-Tetrahydropyran-4-ylamino-5-chloro-1H-indol-2-yl)-phenyl]-acetic acid methyl ester prepared in Example 132 and 1,1-dioxo-thiomorpholine were reacted according to the same procedures as Example 32 and Steps A and B of Example 36 sequentially to give the title compound.