2-Bromo-4-methylaniline → N-(2-bromo-4-methylphenyl)-6-benzothiazolesulfonamide

HRID 2089718Notes

Reaction equation

HRID 2089718 reaction equation
[Br:1][C:2]1[CH:8]=[C:7]([CH3:9])[CH:6]=[CH:5][C:3]=1[NH2:4].[S:10]1[C:14]2[CH:15]=[C:16]([S:19](Cl)(=[O:21])=[O:20])[CH:17]=[CH:18][C:13]=2[N:12]=[CH:11]1>>[Br:1][C:2]1[CH:8]=[C:7]([CH3:9])[CH:6]=[CH:5][C:3]=1[NH:4][S:19]([C:16]1[CH:17]=[CH:18][C:13]2[N:12]=[CH:11][S:10][C:14]=2[CH:15]=1)(=[O:20])=[O:21]

Participants

3

Reactant 2

HCID 114222-Bromo-4-methylanilineHCID 27951701,3-Benzothiazole-6-sulfonyl chloride

Product 1

HCID 67524960N-(2-bromo-4-methylphenyl)-6-benzothiazolesulfonamide

Procedure

By following a procedure analogous to Example 3 starting from 2-bromo-4-methylaniline and 6-benzothiazolesulfonyl chloride, the expected product is obtained in the form of an orange solid (yield=76%).

Sources & evidence

ORD record
ord-21e26ff508a046adb8dab34fa65bd4c8
Source dataset
uspto-grants-2013_05
Patent number
US08436040B2

Reaction notes

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