HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phosphorus oxychloride → 6-broMo-2-chloro-8-fluoroquinoline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phosphorus oxychloride | HCID 24813 | — |
| Reactant | HCID 58349448 | HCID 58349448 | — |
| Product | 6-broMo-2-chloro-8-fluoroquinoline | HCID 58349501 | — |
Reaction Steps
Using the POCl3 procedure from INTERMEDIATE 4 Step B, 6-bromo-8-fluoroquinolone was converted to the title compound: LC6: 3.42 min. (M+H) 260.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08436015B2 |
| Source dataset | uspto-grants-2013_05 |
| ORD ID | ord-a7ab705584334d5781370ac388282475 |
| Source note | uspto-grants-2013_05 |