HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phenyl prop-2-ynoate → Trimesic acid, triphenyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phenyl prop-2-ynoate | HCID 12320093 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | Trimesic acid, triphenyl ester | HCID 522508 | — |
Reaction Steps
In the reaction, phenyl acetylenecarboxylate 12 is readily obtained by a simple condensation of phenol 11 and propiolic acid 9 using 1,3-dicyclohexylcarbodiimine (DCC), 4-(dimethylamino)pyridine (DMAP), 4-toluenesulfonic acid (TsOH) and Dichloromethane (DCM). Refluxing the obtained phenyl acetylenecarboxylate 12 in DMF for 24 hours under nitrogen yields the cyclotrimerized product of triphenyl benzene-1,3,5-tricarboxylate 13.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08436118B2 |
| Source dataset | uspto-grants-2013_05 |
| ORD ID | ord-ad5dfb4afe444c5cb4081eaa1ba613f0 |
| Source note | uspto-grants-2013_05 |