HuagongsheHuagongshe Chemistry Print Report · For research reference only
m-Chloroperbenzoic acid → Methyl thieno[3,4-b]thiophene-2-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | m-Chloroperbenzoic acid | HCID 70297 | — |
| Reactant | Methyl 4,6-dihydrothieno[3,4-b]thiophene-2-carboxylate | HCID 3441857 | — |
| Solvent | Carbon Dioxide | HCID 280 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | Methyl thieno[3,4-b]thiophene-2-carboxylate | HCID 19007653 | — |
Reaction Steps
A solution of 2.0 g (10 mmol) (3) in 30 mL ethyl acetate was stirred and cooled down in dry ice bath. MCPBA (1.75 g, 10 mmol) in 30 mL ethyl acetate was added dropwise to the reaction solution. After the addition, the mixture was kept stirring for overnight. Then the solvent was removed by evaporation and the residue contained a crude product of (4) and 3-chlorobenzoic acid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08436134B2 |
| Source dataset | uspto-grants-2013_05 |
| ORD ID | ord-d13cef28273b45cbaea9509a10853449 |
| Source note | uspto-grants-2013_05 |