HCID 54049649, compound → 3-Ethyl-4-formylbenzonitrile

HRID 2090194Notes

Reaction equation

HRID 2090194 reaction equation
[CH:1]([C:3]1[CH:10]=[CH:9][C:6]([C:7]#[N:8])=[CH:5][C:4]=1[CH:11]=[CH2:12])=[O:2]>C(O)C.[Pd]>[CH2:11]([C:4]1[CH:5]=[C:6]([CH:9]=[CH:10][C:3]=1[CH:1]=[O:2])[C:7]#[N:8])[CH3:12]

Participants

4

Reactant 1

HCID 54049649HCID 54049649, compound

Product 1

HCID 178193273-Ethyl-4-formylbenzonitrile

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

A solution of 1.3 g (8.27 mmol) of 4-formyl-3-vinylbenzonitrile in 35 ml of ethanol is mixed with 880 mg of 10% palladium on carbon and vigorously stirred under a hydrogen atmosphere for 2 h. The suspension is filtered through a layer of kieselguhr, the residue is washed with ethanol, and the filtrate is concentrated. The residue (890 mg) is employed without further purification in the following stage.

Workup

  1. filtrationThe suspension is filtered through a layer of kieselguhr
  2. washthe residue is washed with ethanol
  3. concentrationthe filtrate is concentrated
  4. customThe residue (890 mg) is employed without further purification in the following stage

Sources & evidence

ORD record
ord-20fd7af940644ccda0ad9449634d72c6
Source dataset
uspto-grants-2013_05
Patent number
US08436180B2

Reaction notes

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