HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(7-bromo-3,4-dihydroisoquinolin-2(1H)-yl)-6-(4-methylpiperazin-1-yl)pyrimidin-2-amine → HCID 59402358, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(7-bromo-3,4-dihydroisoquinolin-2(1H)-yl)-6-(4-methylpiperazin-1-yl)pyrimidin-2-amine | HCID 46701048 | — |
| Reactant | 2-Methoxycarbonyl-5-pyridineboronic acid, pinacol ester | HCID 46738663 | — |
| Product | HCID 59402358 | HCID 59402358 | — |
Reaction Steps
This compound was prepared by using procedures analogous to those described for the synthesis of Example 2, starting from 4-(7-bromo-3,4-dihydroisoquinolin-2(1H)-yl)-6-(4-methylpiperazin-1-yl)pyrimidin-2-amine (Example 1) and methyl 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine-2-carboxylate (Frontier Cat. No. M2012). LCMS (M+H)+: m/z=446.3.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08436008B2 |
| Source dataset | uspto-grants-2013_05 |
| ORD ID | ord-500c4ac4963a41dcac9242fd52e21e36 |
| Source note | uspto-grants-2013_05 |