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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2090324Generated: November 1, 2026

Methyl 4-(piperidin-4-yl)benzoate--hydrogen chloride (1/1) → HCID 59402327, compound

https://huagongshe.com/reaction/2090324

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 4-(piperidin-4-yl)benzoate--hydrogen chloride (1/1)HCID 42614593—
Reactant4-(7-bromo-3,4-dihydroisoquinolin-2(1H)-yl)-6-(4-methylpiperazin-1-yl)pyrimidin-2-amineHCID 46701048—
ProductHCID 59402327HCID 59402327—

Reaction Steps

This compound was prepared by using procedures analogous to those described for the synthesis of Example 36 starting from 4-(7-bromo-3,4-dihydroisoquinolin-2(1H)-yl)-6-(4-methylpiperazin-1-yl)pyrimidin-2-amine and methyl 4-(piperidin-4-yl)benzoate hydrochloride (APAC Pharm. LLC, Cat. No. 875920). LCMS (M+H)+: m/z=528.3.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08436008B2
Source datasetuspto-grants-2013_05
ORD IDord-7daedc56b1de4b0594494814a7613d46
Source noteuspto-grants-2013_05