Tert-butyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,2,3,6-tetrahydropyridine-1-carboxylate → HCID 59402379, compound

HRID 2090328Notes

Reaction equation

HRID 2090328 reaction equation
I[C:2]1[CH:7]=[CH:6][N:5]([CH3:8])[C:4](=[O:9])[CH:3]=1.CC1(C)C(C)(C)OB([C:18]2[CH2:19][CH2:20][N:21]([C:24]([O:26][C:27]([CH3:30])([CH3:29])[CH3:28])=[O:25])[CH2:22][CH:23]=2)O1>>[CH3:8][N:5]1[CH:6]=[CH:7][C:2]([C:18]2[CH2:23][CH2:22][N:21]([C:24]([O:26][C:27]([CH3:30])([CH3:29])[CH3:28])=[O:25])[CH2:20][CH:19]=2)=[CH:3][C:4]1=[O:9]

Participants

3

Reactant 2

HCID 4642098Tert-butyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,2,3,6-tetrahydropyridine-1-carboxylateHCID 534080094-Iodo-1-methylpyridin-2(1H)-one

Product 1

HCID 59402379HCID 59402379, compound

Procedure

This compound was prepared by using procedures analogous to those described for the synthesis of Example 2 starting from 4-iodo-1-methylpyridin-2(1H)-one and tert-butyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,6-dihydropyridine-1(2H)-carboxylate (Frontier, Cat. No. P1164). LCMS (M+H)+: m/z=291.1.

Workup

  1. customThis compound was prepared

Sources & evidence

ORD record
ord-3ac0b7eb70134826949e7e751614420a
Source dataset
uspto-grants-2013_05
Patent number
US08436008B2

Reaction notes

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