反应详情

This compound was prepared by using procedures analogous to those described for the synthesis of Example 50A, Step 1 starting from 4-(4-methylpiperazin-1-yl)-6-[3-methyl-7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydroisoquinolin-2(1H)-yl]pyrimidin-2-amine and methyl 4-iodopyridine-2-carboxylate (Combi-Blocks, Cat. No. CA-4128). LCMS (M+H)+: m/z=460.2.

1. customThis compound was prepared