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HRID2090377

反应详情

EQUATION

反应方程式

HRID 2090377 的结构方程式

REACTANTS

反应物

2
结构：CC1(C)OB(c2cnc(C#N)nc2)OC1(C)C
HCID16414276

5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine-2-carbonitrile

C11H14BN3O2

结构：CC1Cc2ccc(Br)cc2CN1c1cc(N2CCN(C)CC2)nc(N)n1
HCID59402317

未命名化合物

PRODUCTS

生成物

1
结构：CC1Cc2ccc(-c3cnc(C#N)nc3)cc2CN1c1cc(N2CCN(C)CC2)nc(N)n1
HCID59402338

未命名化合物

PROCEDURE

实验过程

This compound was prepared by using procedures analogous to those described for the synthesis of Example 50A starting from 4-(7-bromo-3-methyl-3,4-dihydroisoquinolin-2(1H)-yl)-6-(4-methylpiperazin-1-yl)pyrimidin-2-amine (Peak 2, Example 49, Step 7) and 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine-2-carbonitrile (Frontier, Cat. No. C2065). LCMS (M+H)+: m/z=442.2.

WORKUP

后处理

  1. customThis compound was prepared
  2. customthose described for the synthesis of Example 50A