反应详情

The compound was prepared by using procedure analogous to those described for the synthesis of Example 82B, Step 3 starting from 4-(4-methylpiperazin-1-yl)-6-[3-methyl-7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydroisoquinolin-2(1H)-yl]pyrimidin-2-amine and 2-(3-bromo-1H-pyrazol-1-yl)ethanol. LCMS (M+H)+: m/z=449.3.

1. customThe compound was prepared