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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2090456Generated: November 2, 2026

Trifluoroacetic acid → HCID 68471376, compound

https://huagongshe.com/reaction/2090456

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
Reactanttert-butyl N-[(3S)-piperidin-3-yl]carbamateHCID 1514171—
ReactantHCID 59402369HCID 59402369—
ProductHCID 68471376HCID 68471376—

Reaction Steps

This compound was prepared as TFA salt by using procedures analogous to those described for the synthesis of Example 118 starting from 4-chloro-6-[3-methyl-7-(1-methyl-1H-pyrazol-4-yl)-3,4-dihydroisoquinolin-2(1H)-yl]pyrimidin-2-amine and tert-butyl(3S)-piperidin-3-ylcarbamate (CNH Technologies, Cat. No. C-3102S). LCMS (M+H)+: m/z=419.2.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08436008B2
Source datasetuspto-grants-2013_05
ORD IDord-334dfc9f1ffd450eac66b4f2936fdfd1
Source noteuspto-grants-2013_05