HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(Bromomethyl)pyridine hbr → HCID 59402285, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(Bromomethyl)pyridine hbr | HCID 12752219 | — |
| Reactant | 4-(7-bromo-3-methyl-3,4-dihydroisoquinolin-2(1H)-yl)-6-(4-methylpiperazin-1-yl)pyrimidin-2-amine | HCID 59402317 | — |
| Reactant | HCID 178431094 | HCID 178431094 | — |
| Product | HCID 59402285 | HCID 59402285 | — |
Reaction Steps
This compound was prepared by using procedures analogous to those described for the synthesis of Example 156 starting from 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole (Alfa Aesar, Cat. No. H27619), 4-(bromomethyl)-pyridine hydrobromide and 4-(7-bromo-3-methyl-3,4-dihydroisoquinolin-2(1H)-yl)-6-(4-methylpiperazin-1-yl)pyrimidin-2-amine (Peak 1, Example 49, Step 7). LCMS (M+H)+: m/z=496.3.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08436008B2 |
| Source dataset | uspto-grants-2013_05 |
| ORD ID | ord-88c218a0be78440c92197177f53f3e72 |
| Source note | uspto-grants-2013_05 |