HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanol → Ethyl 3-oxohexanoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | 5-butyl-2,2-dimethyl-1,3-dioxane-4,6-dione | HCID 11063445 | — |
| Product | Ethyl 3-oxohexanoate | HCID 238498 | 72% |
Reaction Steps
The 5-butyl-2,2-dimethyl-1,3-dioxane-4,6-dione thus obtained was allowed to reflux in ethanol for 2 hours, and then concentrated under reduced pressure. The resulting residue was purified using silica gel chromatography (developing solvent: n-hexane/ethyl acetate=8/2) to obtain the ethyl 3-oxohexanoate shown by the formula below.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08436210B2 |
| Source dataset | uspto-grants-2013_05 |
| ORD ID | ord-126cd627a5554cf8ad46da2674d9cdd7 |
| Source note | uspto-grants-2013_05 |