Ethyl 3-{[(4-aminophenyl)carbonyl](methyl)amino}propanoate → HCID 66777708, compound

HRID 2090855Notes

Reaction equation

HRID 2090855 reaction equation
[CH:1]1([CH:7]([C:9]2[C:10]([CH3:20])=[N:11][N:12]([C:14]3[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=3)[CH:13]=2)O)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[NH2:21][C:22]1[CH:27]=[CH:26][C:25]([C:28]([N:30]([CH3:38])[CH2:31][CH2:32][C:33]([O:35]CC)=[O:34])=[O:29])=[CH:24][CH:23]=1>>[CH:1]1([CH:7]([NH:21][C:22]2[CH:23]=[CH:24][C:25]([C:28]([N:30]([CH3:38])[CH2:31][CH2:32][C:33]([OH:35])=[O:34])=[O:29])=[CH:26][CH:27]=2)[C:9]2[C:10]([CH3:20])=[N:11][N:12]([C:14]3[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=3)[CH:13]=2)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1

Participants

3

Reactant 2

HCID 46941342Ethyl 3-{[(4-aminophenyl)carbonyl](methyl)amino}propanoateHCID 66778584HCID 66778584, compound

Product 1

HCID 66777708HCID 66777708, compoundYield 23%

Procedure

Using cyclohexyl(3-methyl-1-phenyl-1H-pyrazol-4-yl)methanol (0.14 g) synthesized in Example 17(3) and ethyl 3-{[(4-aminophenyl)carbonyl](methyl)amino}propanoate (0.15 g) synthesized in Example 2(2) and in the same manner as in Example 1(7), the title object compound (0.04 g, 23%) was obtained as a white solid.

Sources & evidence

ORD record
ord-8ced82464ae7408bb19402775c7a0acc
Source dataset
uspto-grants-2013_05
Patent number
US08436043B2

Reaction notes

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