4-(Trifluoromethoxy)phenylboronic acid → HCID 66777478, compound

HRID 2090865Notes

Reaction equation

HRID 2090865 reaction equation
[CH3:1][C:2]1[C:6]([C:7]([O:9][CH3:10])=[O:8])=[CH:5][NH:4][N:3]=1.[F:11][C:12]([F:24])([F:23])[O:13][C:14]1[CH:19]=[CH:18][C:17](B(O)O)=[CH:16][CH:15]=1>>[CH3:1][C:2]1[C:6]([C:7]([O:9][CH3:10])=[O:8])=[CH:5][N:4]([C:17]2[CH:16]=[CH:15][C:14]([O:13][C:12]([F:11])([F:23])[F:24])=[CH:19][CH:18]=2)[N:3]=1

Participants

3

Reactant 2

HCID 27343864-(Trifluoromethoxy)phenylboronic acidHCID 178498883HCID 178498883, compound

Product 1

HCID 66777478HCID 66777478, compoundYield 27%

Procedure

Using methyl 3-methyl-1H-pyrazole-4-carboxylate (6.8 g) synthesized in Example 1(3) and 4-trifluoromethoxyphenylboronic acid (20.0 g) and in the same manner as in Example 17(1), the title object compound (3.9 g, 27%) was obtained as a white solid.

Sources & evidence

ORD record
ord-900fda8bcf684ec19b0442df2a37a95a
Source dataset
uspto-grants-2013_05
Patent number
US08436043B2

Reaction notes

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