HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(Trifluoromethyl)phenylboronic acid → methyl 3-methyl-1-[4-(trifluoromethyl)phenyl]-1H-pyrazole-4-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(Trifluoromethyl)phenylboronic acid | HCID 2734389 | — |
| Reactant | HCID 178498883 | HCID 178498883 | — |
| Product | methyl 3-methyl-1-[4-(trifluoromethyl)phenyl]-1H-pyrazole-4-carboxylate | HCID 66777693 | 11.1% |
Reaction Steps
Using a crude product of methyl 3-methyl-1H-pyrazole-4-carboxylate (8.9 g) synthesized in Example 1(3) and 4-trifluoromethylphenylboronic acid (13.3 g) and in the same manner as in Example 17(1), the title object compound (2.0 g, 11%) was obtained as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08436043B2 |
| Source dataset | uspto-grants-2013_05 |
| ORD ID | ord-f39278d91c0740959fe8d8ea2faf52ec |
| Source note | uspto-grants-2013_05 |