Ethyl 3-(4-aminobenzamido)propanoate → HCID 66776940, compound

HRID 2090885Notes

Reaction equation

HRID 2090885 reaction equation
[CH:1]1([CH:7]([C:9]2[C:10]([CH2:20][O:21][CH3:22])=[N:11][N:12]([C:14]3[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=3)[CH:13]=2)O)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[NH2:23][C:24]1[CH:29]=[CH:28][C:27]([C:30]([NH:32][CH2:33][CH2:34][C:35]([O:37]CC)=[O:36])=[O:31])=[CH:26][CH:25]=1>>[CH:1]1([CH:7]([NH:23][C:24]2[CH:25]=[CH:26][C:27]([C:30]([NH:32][CH2:33][CH2:34][C:35]([OH:37])=[O:36])=[O:31])=[CH:28][CH:29]=2)[C:9]2[C:10]([CH2:20][O:21][CH3:22])=[N:11][N:12]([C:14]3[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=3)[CH:13]=2)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1

Participants

3

Reactant 2

HCID 12469762Ethyl 3-(4-aminobenzamido)propanoateHCID 66777467HCID 66777467, compound

Product 1

HCID 66776940HCID 66776940, compoundYield 46%

Procedure

Using cyclohexyl[3-(methoxymethyl)-1-phenyl-1H-pyrazol-4-yl]methanol (0.50 g) synthesized above and ethyl 3-{[(4-aminophenyl)carbonyl]amino}propanoate (0.39 g) synthesized in Example 1(2) and in the same manner as in Example 1(7), the title object compound (0.37 g, 46%) was obtained as a white solid.

Sources & evidence

ORD record
ord-294f7b53af8e452bb55599f5a65979a1
Source dataset
uspto-grants-2013_05
Patent number
US08436043B2

Reaction notes

Loading…