Ethyl 3-{[(4-aminophenyl)carbonyl](methyl)amino}propanoate → HCID 66777144, compound

HRID 2090891Notes

Reaction equation

HRID 2090891 reaction equation
[CH2:1]([N:8]1[CH:12]=[C:11]([CH:13]([CH:15]2[CH2:20][CH2:19][CH2:18][CH2:17][CH2:16]2)O)[C:10]([CH3:21])=[N:9]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[NH2:22][C:23]1[CH:28]=[CH:27][C:26]([C:29]([N:31]([CH3:39])[CH2:32][CH2:33][C:34]([O:36]CC)=[O:35])=[O:30])=[CH:25][CH:24]=1>>[CH2:1]([N:8]1[CH:12]=[C:11]([CH:13]([NH:22][C:23]2[CH:24]=[CH:25][C:26]([C:29]([N:31]([CH3:39])[CH2:32][CH2:33][C:34]([OH:36])=[O:35])=[O:30])=[CH:27][CH:28]=2)[CH:15]2[CH2:20][CH2:19][CH2:18][CH2:17][CH2:16]2)[C:10]([CH3:21])=[N:9]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 46941342Ethyl 3-{[(4-aminophenyl)carbonyl](methyl)amino}propanoateHCID 66777249HCID 66777249, compound

Product 1

HCID 66777144HCID 66777144, compoundYield 2%

Procedure

Using (1-benzyl-3-methyl-1H-pyrazol-4-yl)(cyclohexyl)methanol (0.65 g) synthesized in Example 41(3) and ethyl 3-{[(4-aminophenyl)carbonyl](methyl)amino}propanoate (0.65 g) synthesized in Example 2(2) and in the same manner as in Example 1(7), the title object compound (18.2 mg, 2%) was obtained as a white solid.

Sources & evidence

ORD record
ord-eb788422c32a41dc989e25cc685867eb
Source dataset
uspto-grants-2013_05
Patent number
US08436043B2

Reaction notes

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