Ethyl 3-(4-aminobenzamido)propanoate → HCID 66777707, compound

HRID 2090893Notes

Reaction equation

HRID 2090893 reaction equation
[CH:1]1([CH:7]([C:9]2[C:10]([CH3:19])=[N:11][N:12]([C:14]([CH3:18])([CH3:17])[CH2:15][CH3:16])[CH:13]=2)O)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[NH2:20][C:21]1[CH:26]=[CH:25][C:24]([C:27]([NH:29][CH2:30][CH2:31][C:32]([O:34]CC)=[O:33])=[O:28])=[CH:23][CH:22]=1>>[CH:1]1([CH:7]([NH:20][C:21]2[CH:22]=[CH:23][C:24]([C:27]([NH:29][CH2:30][CH2:31][C:32]([OH:34])=[O:33])=[O:28])=[CH:25][CH:26]=2)[C:9]2[C:10]([CH3:19])=[N:11][N:12]([C:14]([CH3:18])([CH3:17])[CH2:15][CH3:16])[CH:13]=2)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1

Participants

3

Reactant 2

HCID 12469762Ethyl 3-(4-aminobenzamido)propanoateHCID 66778407HCID 66778407, compound

Product 1

HCID 66777707HCID 66777707, compoundYield 46%

Procedure

Using cyclohexyl[1-(1,1-dimethylpropyl)-3-methyl-1H-pyrazol-4-yl]methanol (1.0 g) synthesized above and ethyl 3-{[(4-aminophenyl)carbonyl]amino}propanoate (0.67 g) synthesized in Example 1(2) and in the same manner as in Example 1(7), the title object compound (0.41 g, 46%) was obtained as a white solid.

Sources & evidence

ORD record
ord-234d04b721c648b7b20c147b13f89807
Source dataset
uspto-grants-2013_05
Patent number
US08436043B2

Reaction notes

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