Ethyl 3-{[(4-aminophenyl)carbonyl](methyl)amino}propanoate → HCID 66777512, compound

HRID 2090901Notes

Reaction equation

HRID 2090901 reaction equation
[CH2:1]([C:3]1[C:7]([CH:8](O)[CH2:9][CH:10]([CH3:12])[CH3:11])=[CH:6][N:5]([C:14]2[CH:19]=[CH:18][C:17]([O:20][CH3:21])=[CH:16][CH:15]=2)[N:4]=1)[CH3:2].[NH2:22][C:23]1[CH:28]=[CH:27][C:26]([C:29]([N:31]([CH3:39])[CH2:32][CH2:33][C:34]([O:36]CC)=[O:35])=[O:30])=[CH:25][CH:24]=1>>[CH2:1]([C:3]1[C:7]([CH:8]([NH:22][C:23]2[CH:24]=[CH:25][C:26]([C:29]([N:31]([CH3:39])[CH2:32][CH2:33][C:34]([OH:36])=[O:35])=[O:30])=[CH:27][CH:28]=2)[CH2:9][CH:10]([CH3:12])[CH3:11])=[CH:6][N:5]([C:14]2[CH:19]=[CH:18][C:17]([O:20][CH3:21])=[CH:16][CH:15]=2)[N:4]=1)[CH3:2]

Participants

3

Reactant 2

HCID 46941342Ethyl 3-{[(4-aminophenyl)carbonyl](methyl)amino}propanoateHCID 66778620HCID 66778620, compound

Product 1

HCID 66777512HCID 66777512, compoundYield 12%

Procedure

Using 1-[3-ethyl-1-(4-methoxyphenyl)-1H-pyrazol-4-yl]-3-methylbutan-1-ol (0.5 g) synthesized in Example 48(3) and ethyl 3-{[(4-aminophenyl)carbonyl](methyl)amino}propanoate (0.44 g) synthesized in Example 2(2) and in the same manner as in Example 1(7), the title object compound (0.1 g, 12%) was obtained as a white solid.

Sources & evidence

ORD record
ord-cb61e98f9c0a47a58db0c93fe8379a4b
Source dataset
uspto-grants-2013_05
Patent number
US08436043B2

Reaction notes

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