Ethyl 3-(methylamino)propanoate → HCID 66776993, compound

HRID 2090981Notes

Reaction equation

HRID 2090981 reaction equation
[S:1]1[C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=2[CH:3]=[C:2]1[CH:10]([NH:17][C:18]1[CH:26]=[CH:25][C:21]([C:22](O)=[O:23])=[CH:20][CH:19]=1)[CH:11]1[CH2:16][CH2:15][CH2:14][CH2:13][CH2:12]1.[CH3:27][NH:28][CH2:29][CH2:30][C:31]([O:33]CC)=[O:32]>>[S:1]1[C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=2[CH:3]=[C:2]1[CH:10]([NH:17][C:18]1[CH:19]=[CH:20][C:21]([C:22]([N:28]([CH3:27])[CH2:29][CH2:30][C:31]([OH:33])=[O:32])=[O:23])=[CH:25][CH:26]=1)[CH:11]1[CH2:12][CH2:13][CH2:14][CH2:15][CH2:16]1

Participants

3

Reactant 2

HCID 541480Ethyl 3-(methylamino)propanoateHCID 66777879HCID 66777879, compound

Product 1

HCID 66776993HCID 66776993, compound

Procedure

Using 4-{[1-benzothiophen-2-yl(cyclohexyl)methyl]amino}benzoic acid (250 mg) synthesized above and ethyl 3-(methylamino)propanoate (108 mg) and in the same manner as in Example A1(4), the title object compound (277 mg, 90%) was obtained as a white solid.

Sources & evidence

ORD record
ord-05dfec84f524459b85bda2e014d3711e
Source dataset
uspto-grants-2013_05
Patent number
US08436043B2

Reaction notes

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