Potassium Cation → 6-bromo-2-(4-tert-butoxycarbonylbenzyl)-1-oxo-4-phenyl-1,2-dihydroisoquinoline-3-carboxylic Acid Methyl Ester

HRID 209099Notes

Reaction equation

HRID 209099 reaction equation
[C:33]([CH3:34])([CH3:35])([CH3:36])[O:37][C:38](=[NH:39])[C:40]([Cl:41])([Cl:42])[Cl:43].[C:44](=[O:45])([O-:46])[O-:47].[CH2:50]([Cl:51])[Cl:52].[CH3:1][O:2][C:3](=[O:4])[c:5]1[n:6]([CH2:23][c:24]2[cH:25][cH:26][c:27]([C:30](=[O:31])[OH:32])[cH:28][cH:29]2)[c:7](=[O:22])[c:8]2[cH:9][cH:10][c:11]([Br:21])[cH:12][c:13]2[c:14]1-[c:15]1[cH:16][cH:17][cH:18][cH:19][cH:20]1.[K+:48].[K+:49]>>[CH3:1][O:2][C:3](=[O:4])[c:5]1[n:6]([CH2:23][c:24]2[cH:25][cH:26][c:27]([C:30](=[O:31])[O:32][C:33]([CH3:34])([CH3:35])[CH3:36])[cH:28][cH:29]2)[c:7](=[O:22])[c:8]2[cH:9][cH:10][c:11]([Br:21])[cH:12][c:13]2[c:14]1-[c:15]1[cH:16][cH:17][cH:18][cH:19][cH:20]1

Participants

6

Reactant 5

HCID 813Potassium Cation2×HCID 6344DichloromethaneHCID 19660Carbonate IonHCID 2734700Tert-butyl 2,2,2-trichloroethanimidateHCID 102890466-bromo-2-(4-carboxybenzyl)-1-oxo-4-phenyl-1,2-dihydroisoquinoline-3-carboxylic Acid Methyl Ester

Product 1

HCID 691566226-bromo-2-(4-tert-butoxycarbonylbenzyl)-1-oxo-4-phenyl-1,2-dihydroisoquinoline-3-carboxylic Acid Methyl Ester

Sources & evidence

ORD record
ord-2ced562e514b4afcaa1e9b6dc1809812
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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