Ethyl 3-{[(4-aminophenyl)carbonyl](methyl)amino}propanoate → HCID 44227312, compound

HRID 2090996Notes

Reaction equation

HRID 2090996 reaction equation
Cl[CH:2]([CH:13]1[CH2:18][CH2:17][CH2:16][CH2:15][CH2:14]1)[C:3]1[O:4][C:5]2[CH:12]=[CH:11][CH:10]=[CH:9][C:6]=2[C:7]=1[CH3:8].[NH2:19][C:20]1[CH:25]=[CH:24][C:23]([C:26]([N:28]([CH3:36])[CH2:29][CH2:30][C:31]([O:33]CC)=[O:32])=[O:27])=[CH:22][CH:21]=1>>[CH:13]1([CH:2]([NH:19][C:20]2[CH:21]=[CH:22][C:23]([C:26]([N:28]([CH3:36])[CH2:29][CH2:30][C:31]([OH:33])=[O:32])=[O:27])=[CH:24][CH:25]=2)[C:3]2[O:4][C:5]3[CH:12]=[CH:11][CH:10]=[CH:9][C:6]=3[C:7]=2[CH3:8])[CH2:18][CH2:17][CH2:16][CH2:15][CH2:14]1

Participants

3

Reactant 2

HCID 46941342Ethyl 3-{[(4-aminophenyl)carbonyl](methyl)amino}propanoateHCID 66777149HCID 66777149, compound

Product 1

HCID 44227312HCID 44227312, compound

Procedure

Using 2-[chloro(cyclohexyl)methyl]-3-methyl-1-benzofuran (429 mg) synthesized above and ethyl 3-{[(4-aminophenyl)carbonyl](methyl)amino}propanoate (408 mg) synthesized in Example 2(2) and in the same manner as in Example A7(3), the title object compound (247 mg, 34%) was obtained as a white solid.

Sources & evidence

ORD record
ord-8bc411783e56482e874d029fa17034a1
Source dataset
uspto-grants-2013_05
Patent number
US08436043B2

Reaction notes

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