Ethyl 3-(4-aminobenzamido)propanoate → HCID 66777543, compound

HRID 2091000Notes

Reaction equation

HRID 2091000 reaction equation
Cl[CH:2]([CH:14]1[CH2:19][CH2:18][CH2:17][CH2:16][CH2:15]1)[C:3]1[O:4][C:5]2[C:11]([O:12][CH3:13])=[CH:10][CH:9]=[CH:8][C:6]=2[CH:7]=1.[NH2:20][C:21]1[CH:26]=[CH:25][C:24]([C:27]([NH:29][CH2:30][CH2:31][C:32]([O:34]CC)=[O:33])=[O:28])=[CH:23][CH:22]=1>>[CH:14]1([CH:2]([NH:20][C:21]2[CH:22]=[CH:23][C:24]([C:27]([NH:29][CH2:30][CH2:31][C:32]([OH:34])=[O:33])=[O:28])=[CH:25][CH:26]=2)[C:3]2[O:4][C:5]3[C:11]([O:12][CH3:13])=[CH:10][CH:9]=[CH:8][C:6]=3[CH:7]=2)[CH2:19][CH2:18][CH2:17][CH2:16][CH2:15]1

Participants

3

Reactant 2

HCID 12469762Ethyl 3-(4-aminobenzamido)propanoateHCID 66777980HCID 66777980, compound

Product 1

HCID 66777543HCID 66777543, compound

Procedure

Using 2-[chloro(cyclohexyl)methyl]-7-methoxy-1-benzofuran (422 mg) synthesized above and ethyl 3-{[(4-aminophenyl)carbonyl]amino}propanoate (357 mg) synthesized in Example 1(2) and in the same manner as in Example A7(3), the title object compound (64.3 mg, 9%) was obtained as a pale-yellow solid.

Sources & evidence

ORD record
ord-a77b7af96ac7492ca16802e2c142706f
Source dataset
uspto-grants-2013_05
Patent number
US08436043B2

Reaction notes

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