Ethyl 3-{[(4-aminophenyl)carbonyl](methyl)amino}propanoate → HCID 66777908, compound

HRID 2091030Notes

Reaction equation

HRID 2091030 reaction equation
[CH:1]1([CH:7]([C:9]2[N:10]=[C:11]3[CH:16]=[CH:15][C:14]([C:17]([F:20])([F:19])[F:18])=[CH:13][N:12]3[CH:21]=2)O)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[NH2:22][C:23]1[CH:28]=[CH:27][C:26]([C:29]([N:31]([CH3:39])[CH2:32][CH2:33][C:34]([O:36]CC)=[O:35])=[O:30])=[CH:25][CH:24]=1>>[CH:1]1([CH:7]([NH:22][C:23]2[CH:24]=[CH:25][C:26]([C:29]([N:31]([CH3:39])[CH2:32][CH2:33][C:34]([OH:36])=[O:35])=[O:30])=[CH:27][CH:28]=2)[C:9]2[N:10]=[C:11]3[CH:16]=[CH:15][C:14]([C:17]([F:20])([F:19])[F:18])=[CH:13][N:12]3[CH:21]=2)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1

Participants

3

Reactant 2

HCID 46941342Ethyl 3-{[(4-aminophenyl)carbonyl](methyl)amino}propanoateHCID 66778779HCID 66778779, compound

Product 1

HCID 66777908HCID 66777908, compoundYield 2%

Procedure

Using cyclohexyl[6-(trifluoromethyl)imidazo[1,2-a]pyridin-2-yl]methanol (1.1 g) synthesized above and ethyl 3-{[(4-aminophenyl)carbonyl](methyl)amino}propanoate (0.94 g) synthesized in Example 2(2) and in the same manner as in Example 4, the title object compound (3.0 mg, 2%) was obtained as an oil.

Sources & evidence

ORD record
ord-86004a69583b45d4851af958a5940d37
Source dataset
uspto-grants-2013_05
Patent number
US08436043B2

Reaction notes

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