HCID 66777037, compound → HCID 66777135, compound

Participants

Reaction Conditions

Reaction Steps

[5-(Benzyloxy)-3-methyl-1-benzofuran-2-yl](cyclohexyl)methanone (7.3 g) synthesized in the above-mentioned (2) was dissolved in a ethanol (150 mL) and tetrahydrofuran (30 mL), and palladium carbon-ethylenediamine complex (1.0 g) was added at room temperature. The reaction mixture was stirred at 60° C. for 3 hr under hydrogen atmosphere (1 atm), allowed to cool to room temperature, and the catalyst was filtered. The filtrate was concentrated under reduced pressure to give a crude product (5.2 g, quantitative) of the title object compound as a colorless solid.

Provenance & Evidence