Methyl morpholine oxide → HCID 86662751, compound

Participants

Reaction Steps

To a mixture of {5-fluoro-3-[(2-methoxyethoxy)methyl]-1-benzofuran-2-yl}methanol (2.65 g) synthesized above, 4-methylmorpholine N-oxide (2.44 g) and acetonitrile (50 mL) was added tetrapropylammonium perruthenate (366 mg), and the mixture was stirred for 5 hr, and concentrated under reduced pressure. The residue was purified by silica gel column chromatography (0-30% ethyl acetate/hexane) to give the title object compound (1.33 g, 51%) as a yellow oil.

Provenance & Evidence