Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2091369Generated: October 31, 2026

Sodium Hydroxide → HCID 66777830, compound

https://huagongshe.com/reaction/2091369

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium HydroxideHCID 14798—
ReactantHCID 66778745HCID 66778745—
SolventEthanolHCID 702—
ProductHCID 66777830HCID 6677783089%

Reaction Steps

Ethyl 3-({[4-({1-[5-(benzyloxy)-3-methyl-1-benzofuran-2-yl]-2-methylpropyl}amino)phenyl]carbonyl}amino)propanoate (0.43 g) synthesized in the above-mentioned (1) was dissolved in ethanol (10 mL), 1N aqueous sodium hydroxide solution (2.0 mL) was added to the solution at room temperature, and the mixture was stirred at room temperature for 0.5 hr. Ethanol was evaporated under reduced pressure, and 1N hydrochloric acid (2.0 mL) was added to the residue. The precipitate was washed with water to give the title object compound (0.36 g, 89%) as a colorless solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08436043B2
Source datasetuspto-grants-2013_05
ORD IDord-e9913bd409634f30b2a9b2240a59e2f9
Source noteuspto-grants-2013_05