反应详情

To a solution of 1-[5-(benzyloxy)-3-methyl-1-benzofuran-2-yl]-2-methylpropan-1-one (11.4 g) synthesized in Example A85(1) in ethanol (200 mL) was added palladium carbon-ethylenediamine complex (1.1 g) at room temperature. The reaction mixture was stirred under hydrogen atmosphere (1 atm) at room temperature for 16 hr, and the catalyst was filtered off. The filtrate was concentrated under reduced pressure to give a crude product (8.0 g, quantitative) of the title object compound as a colorless solid.

1. additionwas added palladium carbon-ethylenediamine complex (1.1 g) at room temperature
2. filtrationthe catalyst was filtered off
3. concentrationThe filtrate was concentrated under reduced pressure