HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 178420347, compound → HCID 178511561, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 178420347 | HCID 178420347 | — |
| Catalyst | Palladium hydroxide | HCID 9942167 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 178511561 | HCID 178511561 | — |
Reaction Steps
cis-N,N-Dibenzyl-N-{4-[(2-piperidylethoxy)methyl]cyclohexyl}amine (2.84 g, 6.65 mmol) was dissolved in 20 mL of ethanol. Palladium hydroxide (20% weight) was added (50 mg) and the reaction was stirred overnight under an atmosphere of hydrogen. The catalyst was removed by filtration and washed with small portions of ethanol. The filtrate was concentrated and used without further purification. (quantitative yield): ES-MS (m/z) 241.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08440661B2 |
| Source dataset | uspto-grants-2013_05 |
| ORD ID | ord-458432eeec194680b8ace6a2fa3d5c53 |
| Source note | uspto-grants-2013_05 |