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HRID2091743

反应详情

EQUATION

反应方程式

HRID 2091743 的结构方程式

REACTANTS

反应物

2
结构：COC(=O)c1cncc(Br)c1
HCID699336

Methyl 5-bromonicotinate

C7H6BrNO2

结构：OB(O)c1ccc(C(F)(F)F)cc1
HCID2734389

4-(Trifluoromethyl)phenylboronic acid

C7H6BF3O2

PRODUCTS

生成物

1
结构：COC(=O)c1cncc(-c2ccc(C(F)(F)F)cc2)c1
HCID20099855

Methyl 5-[4-(trifluoromethyl)phenyl]pyridine-3-carboxylate

C14H10F3NO2

PROCEDURE

实验过程

According to General Method 3A, 28 g (132 mmol) of methyl 5-bromonicotinate and 30 g (158 mmol, 1.2 eq.) of 4-trifluoromethylphenylboronic acid were reacted. Yield: 32 g (85% of theory)

WORKUP

后处理

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