HuagongsheHuagongshe Chemistry Print Report · For research reference only
(6-Aminopyridin-3-yl)boronic acid → HCID 53378375, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (6-Aminopyridin-3-yl)boronic acid | HCID 22396308 | — |
| Reactant | 2-(1-((2-Chloro-4-morpholinopyrido[3,2-d]pyrimidin-6-yl)methyl)piperidin-4-yl)propan-2-ol | HCID 58404970 | — |
| Product | HCID 53378375 | HCID 53378375 | — |
Reaction Steps
2-(1-((2-Chloro-4-morpholinopyrido[3,2-d]pyrimidin-6-yl)methyl)piperidin-4-yl)propan-2-ol from Example 8 (0.1 g) was reacted with 2-aminopyridine-5-boronic acid, pinacol ester via General Procedure A to yield 40.3 mg 122 following reverse phase HPLC purification. MS (Q1) 464.3 (M)+
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08440651B2 |
| Source dataset | uspto-grants-2013_05 |
| ORD ID | ord-be5ac49c463d4861918287647d1e5178 |
| Source note | uspto-grants-2013_05 |