HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(difluoromethyl)-1H-1,3-benzodiazole → HCID 53377725, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(difluoromethyl)-1H-1,3-benzodiazole | HCID 597703 | — |
| Reactant | 4-(1-((2-Chloro-4-morpholinopyrido[3,2-d]pyrimidin-6-yl)methyl)azetidin-3-yl)morpholine | HCID 58405030 | — |
| Product | HCID 53377725 | HCID 53377725 | — |
Reaction Steps
4-(1-((2-chloro-4-morpholinopyrido[3,2-d]pyrimidin-6-yl)methyl)azetidin-3-yl)morpholine from Example 126 (0.07 g) was reacted with 2-(difluoromethyl)-1H-benzo[d]imidazole via General Procedure D to produce 10.7 mg of 172 following reverse phase HPLC purification. MS (Q1) 537.2 (M)+
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08440651B2 |
| Source dataset | uspto-grants-2013_05 |
| ORD ID | ord-502743325f494f55b16171dac9e048a2 |
| Source note | uspto-grants-2013_05 |